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Head-to-head · WeighScore

1st Optimal vs MD Trim Clinic

1st Optimal
Graded #288

Higher grade

vs+5.5
MD Trim Clinic
Graded #421

Lower grade

The verdict

1st Optimal takes it — 61.6/100 to 56.1/100.

1st Optimal grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. 1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulation1st Optimal +11
51
40
Clinical oversightMD Trim Clinic +3
77
80
Labs & monitoring1st Optimal +34
97
63
Fulfillment1st Optimal +2
60
58
Contract termsMD Trim Clinic +18
37
55
1st Optimal · left barMD Trim Clinic · right bar

The numbers

Metric1st OptimalMD Trim Clinic
WeighScore61.6/10056.1/100
GradeCC
Scorecard rank#288#421
SemaglutideNot disclosedNot disclosed
TirzepatideNot disclosedNot disclosed
CoverageCoverage not published2 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
1st Optimal

Graded #288 · C

Strengths

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where it loses points

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation
MD Trim Clinic

Graded #421 · C

Strengths

  • Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
  • Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
  • Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
  • Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
  • Partnered mobile IV services available for enhanced nausea management and hydration support

Where it loses points

  • Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
  • Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
  • No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
  • Small practice with limited online presence and no published patient reviews or outcomes data
  • No labs, coaching, or monitoring protocols disclosed on the site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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