Head-to-head · WeighScore
1st Optimal vs MANÜ Telehealth
The verdict
MANÜ Telehealth takes it — 72.2/100 to 61.6/100.
MANÜ Telehealth grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MANÜ Telehealth is a US online platform offering compounded GLP-1 weight loss medication including injectable tirzepatide and semaglutide, with add-ons like MIC Ultraburn and NAD+ injections.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | MANÜ Telehealth |
|---|---|---|
| WeighScore | 61.6/100 | 72.2/100 |
| Grade | C | C |
| Scorecard rank | #288 | #83 |
| Semaglutide | Not disclosed | $120/mo (compounded) |
| Tirzepatide | Not disclosed | $150/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #288 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #83 · C
Strengths
- Compounded GLP-1s advertised from about $4-$5/day
- 100% online with free discreet shipping and no insurance needed
- Compounds exclusively from US 503A pharmacies
- Add-on options like MIC Ultraburn and NAD+
Where it loses points
- Per-dose pricing is gated behind login/signup, not public
- State availability changes and is only confirmed at signup
- Compounded medications are not FDA-evaluated
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.