Head-to-head · WeighScore
1st Optimal vs LevelUp Rx
The verdict
LevelUp Rx takes it — 64.2/100 to 61.6/100.
LevelUp Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LevelUp Rx is a telehealth pharmacy offering compounded GLP-1 weight-loss medications - compounded semaglutide and compounded tirzepatide - alongside a broad menu of men's and women's health treatments.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | LevelUp Rx |
|---|---|---|
| WeighScore | 61.6/100 | 64.2/100 |
| Grade | C | C |
| Scorecard rank | #291 | #245 |
| Semaglutide | Not disclosed | $150/mo (starting dose, compounded) |
| Tirzepatide | Not disclosed | $250/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #245 · C
Strengths
- Compounded semaglutide ($149.97/mo) and tirzepatide ($249.97/mo) on one platform
- Flat monthly price that never changes with your dose
- No-cost online consultation included with your order
- LegitScript-certified; partner pharmacies named (DiRx and The DrugStore)
- Free shipping with no insurance required
Where it loses points
- Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro
- No single prescribing medical group named; physicians listed only for CA, MA, RI and VT
- State availability is confirmed during intake, not published as a list
- Prescription sales are final once shipped; no returns on dispensed medication
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.