Head-to-head · WeighScore
1st Optimal vs InstaRX
The verdict
InstaRX takes it — 63.8/100 to 61.6/100.
InstaRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. InstaRX is a multi-product compounded-medication telehealth platform offering GLP-1 injections (semaglutide and tirzepatide) alongside anti-aging peptides (NAD+, Sermorelin, B12/MIC) and sexual-health…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | InstaRX |
|---|---|---|
| WeighScore | 61.6/100 | 63.8/100 |
| Grade | C | C |
| Scorecard rank | #291 | #253 |
| Semaglutide | Not disclosed | $199/mo (starting dose, compounded) |
| Tirzepatide | Not disclosed | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #253 · C
Strengths
- Available in all 50 states plus DC
- Manage GLP-1, anti-aging peptides, and sexual-health medications on one account
- Offers both compounded semaglutide and compounded tirzepatide
- Independent provider group (Dr Telx) named in the Terms of Service
Where it loses points
- No per-dose or monthly pricing published — only a "$199 to get started" hook; you can't compare costs before intake
- No LegitScript, HIPAA, or NABP accreditation shown on public pages
- Compounding pharmacy not named — only "U.S. pharmacies"
- Terms of Service reads like generic boilerplate, including copy-paste language about women's health issues — suggests low template hygiene
- Delaware governing law for disputes despite a California corporate address
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.