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Head-to-head · WeighScore

1st Optimal vs Curex

1st Optimal
Graded #291

Lower grade

vs+7.600000000000001
Curex
Graded #135

Higher grade

The verdict

Curex takes it — 69.2/100 to 61.6/100.

Curex grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Curex (Curex, Inc.) offers compounded semaglutide ($149/mo) and tirzepatide ($199/mo) in injectable and oral dissolving tablet formats.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCurex +9
45
54
Dose & formulationCurex +24
51
75
Clinical oversightCurex +7
77
84
Labs & monitoring1st Optimal +42
97
55
FulfillmentCurex +30
60
90
Contract termsCurex +24
37
61
1st Optimal · left barCurex · right bar

The numbers

Metric1st OptimalCurex
WeighScore61.6/10069.2/100
GradeCC
Scorecard rank#291#135
SemaglutideNot disclosed$199/mo (compounded oral)
TirzepatideNot disclosed$199/mo (compounded oral)
CoverageCoverage not published45 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
1st Optimal

Graded #291 · C

Strengths

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where it loses points

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation
Curex

Graded #135 · C

Strengths

  • LegitScript certified
  • Named entity (Curex, Inc.) with two offices — Miami FL and NYC
  • No membership fee ever
  • Injectable and oral dissolving tablet formats
  • Third-party lab testing via FDA/DEA certified labs

Where it loses points

  • Not available in AK, AR, CT, HI, MA, NM, MO
  • Compounded only — explicitly states 'We don't prescribe Ozempic, Wegovy, Zepbound, or Mounjaro'
  • Primary business is allergy immunotherapy — GLP-1 is a newer vertical

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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