Head-to-head · WeighScore
1st Optimal vs Cielo
The verdict
Cielo takes it — 69.4/100 to 61.6/100.
Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | Cielo |
|---|---|---|
| WeighScore | 61.6/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #291 | #127 |
| Semaglutide | Not disclosed | $149/mo (all doses, compounded) |
| Tirzepatide | Not disclosed | $249/mo (all doses, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #127 · C
Strengths
- Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
- Single flat price across all doses simplifies titration planning
- Corporate address (St. Petersburg, FL) and customer-service phone published
Where it loses points
- No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
- Pharmacy partner not named (only 'regulated FDA pharmacy partners')
- State coverage list not published — can't verify all-50-state availability
- Clinical care runs through MD Integrations, a shared third-party network used by many brands
- No brand-name Wegovy or Zepbound option
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.