Head-to-head · WeighScore
1st Optimal vs Center for Medical Weight Loss (CMWL)
The verdict
Center for Medical Weight Loss (CMWL) takes it — 66.9/100 to 61.6/100.
Center for Medical Weight Loss (CMWL) grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Center for Medical Weight Loss (CMWL) runs a 100 percent online, physician-supervised GLP-1 program using compounded semaglutide and tirzepatide with flat any-dose pricing.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | Center for Medical Weight Loss (CMWL) |
|---|---|---|
| WeighScore | 61.6/100 | 66.9/100 |
| Grade | C | C |
| Scorecard rank | #288 | #171 |
| Semaglutide | Not disclosed | $149/mo (all doses, compounded) |
| Tirzepatide | Not disclosed | $239/mo (all doses, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #288 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #171 · C
Strengths
- Very competitive flat any-dose pricing (semaglutide from 116 dollars per month, tirzepatide from 159 dollars per month)
- Established Center for Medical Weight Loss brand with physician supervision and clinical support
- Fast 24-hour approvals and free three to five day shipping
Where it loses points
- Some states are ineligible and the eligible-state list is not published
- Compounding pharmacy is not named publicly
- Lowest per-month prices require a three-month prepaid commitment
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.