Head-to-head · WeighScore
1st Optimal vs BetterMe Rx
The verdict
BetterMe Rx takes it — 64.9/100 to 61.6/100.
BetterMe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. BetterMe Rx offers compounded semaglutide ($199/mo) and tirzepatide ($299/mo) in both injectable and oral daily tablet formats.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | BetterMe Rx |
|---|---|---|
| WeighScore | 61.6/100 | 64.9/100 |
| Grade | C | C |
| Scorecard rank | #291 | #236 |
| Semaglutide | Not disclosed | $199/mo (promotional rate, compounded) |
| Tirzepatide | Not disclosed | $299/mo (promotional rate, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #291 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #236 · C
Strengths
- LegitScript verified
- All 50 states coverage
- Six named pharmacy partners with phone numbers — exceptional transparency
- Both injectable and oral daily tablet formats for sema and tirz
- Multi-month discounts (3-month and 6-month plans)
Where it loses points
- No formal corporate entity name or address disclosed
- Compounded only — no brand-name options
- Broader platform (HRT, ED, NAD+, Sermorelin, skincare)
- Headline $199/$299 are limited-time SALE prices; regular prices are $249/$349 per month
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.