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Head-to-head · WeighScore

1st Optimal vs AskRx

1st Optimal
Graded #291

Higher grade

vs+5.800000000000004
AskRx
Graded #430

Lower grade

The verdict

1st Optimal takes it — 61.6/100 to 55.8/100.

1st Optimal grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. 1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost value1st Optimal +21
45
24
Dose & formulationAskRx +16
51
67
Clinical oversightAskRx +5
77
82
Labs & monitoring1st Optimal +45
97
52
FulfillmentAskRx +28
60
88
Contract terms1st Optimal +17
37
20
1st Optimal · left barAskRx · right bar

The numbers

Metric1st OptimalAskRx
WeighScore61.6/10055.8/100
GradeCC
Scorecard rank#291#430
SemaglutideNot disclosed$349/mo (all doses, brand-name)
TirzepatideNot disclosed$299/mo (2.5 mg dose, brand-name)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesInjection only
1st Optimal

Graded #291 · C

Strengths

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where it loses points

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation
AskRx

Graded #430 · C

Strengths

  • Prescribes only FDA-approved brand-name GLP-1s, no compounded drugs
  • LegitScript approved and HIPAA compliant
  • Board-certified physicians trained in obesity medicine
  • Transparent dose-based pricing published on site
  • Available in all 50 states

Where it loses points

  • Cash-pay model; medication cost billed separately by the pharmacy
  • Does not dispense medication itself, so fulfillment depends on third-party pharmacies
  • No compounded lower-cost alternative offered
  • Specific list of supported states is not published

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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