Head-to-head · WeighScore
TRT Nation vs Youth & Soul
The verdict
TRT Nation takes it — 63.1/100 to 61.6/100, but only just.
TRT Nation grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. TRT Nation is a men's telehealth platform focused primarily on testosterone replacement therapy, with compounded GLP-1 weight loss as a secondary vertical. Youth & Soul is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | TRT Nation | Youth & Soul |
|---|---|---|
| WeighScore | 63.1/100 | 61.6/100 |
| Grade | C | C |
| Scorecard rank | #260 | #291 |
| Semaglutide | Not disclosed | $149/mo (starting dose, compounded) |
| Tirzepatide | $219/mo | $399/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #260 · C
Strengths
- Flat $219/mo tirzepatide regardless of dose escalation
- Tirzepatide compounded with B12 to reduce nausea
- Flat plan includes unlimited virtual provider visits
- Fully online intake-to-delivery process
- Compounded from licensed US pharmacies
Where it loses points
- Weight loss is secondary to core TRT business
- Specific pharmacy partner and 503A status not disclosed
- Compounded only; not FDA-approved formulations
- State licensing list not published
Graded #291 · C
Strengths
- Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
- Full refund advertised if you are not approved
- Physician consultation, prescription and shipping stated as included in the plan price
- Ten treatment verticals under one account, from GLP-1 to HRT, peptides and mental health
Where it loses points
- Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
- Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
- Its own copy promises never to fabricate testimonials while displaying those scraped comments
- Homepage trust counters render as 0K+ medical professionals, 0.0M+ patients and 0M+ successful orders
- Labels its compounded tirzepatide a Mounjaro compound, conflating a compounded drug with the brand
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.