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Head-to-head · WeighScore

Trillium Meds vs ZYP Medical

Trillium Meds
Graded #124

Lower grade

vs+5.199999999999989
ZYP Medical
Graded #62

Higher grade

The verdict

ZYP Medical takes it — 74.6/100 to 69.4/100.

ZYP Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZYP Medical +10
70
80
Dose & formulationZYP Medical +19
64
83
Clinical oversightZYP Medical +2
84
86
Labs & monitoringTrillium Meds +22
75
53
FulfillmentTrillium Meds +13
79
66
Contract termsZYP Medical +41
20
61
Trillium Meds · left barZYP Medical · right bar

The numbers

MetricTrillium MedsZYP Medical
WeighScore69.4/10074.6/100
GradeCC
Scorecard rank#124#62
Semaglutide$119/mo (3-month plan, compounded)$150/mo
Tirzepatide$199/mo (3-month plan, compounded)$233/mo
CoverageAll 50 states6 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Trillium Meds

Graded #124 · C

Strengths

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

Where it loses points

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network
ZYP Medical

Graded #62 · C

Strengths

  • Transparent flat-rate pricing including medication and shipping with no hidden fees
  • Low $50 initial one-hour consultation
  • Offers both injectable and oral tirzepatide options
  • No membership fees and pricing decreases as treatment progresses
  • Care from a board-certified family nurse practitioner

Where it loses points

  • Compounded medications are not FDA-approved
  • Available in only six states (NE, IA, SD, KS, CO, AZ)
  • Cash-pay only; no insurance noted
  • No named compounding pharmacy partner disclosed
  • No LegitScript certification shown on site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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