Head-to-head · WeighScore
Synergy Rx vs ZYP Medical
The verdict
Synergy Rx takes it — 76.2/100 to 74.3/100, but only just.
Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact. ZYP Medical is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Synergy Rx | ZYP Medical |
|---|---|---|
| WeighScore | 76.2/100 | 74.3/100 |
| Grade | C | C |
| Scorecard rank | #41 | #66 |
| Semaglutide | From $199/mo | $150/mo |
| Tirzepatide | From $349/mo | $233/mo |
| Coverage | Not disclosed | 6 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #41 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Graded #66 · C
Strengths
- Transparent flat-rate pricing including medication and shipping with no hidden fees
- Low $50 initial one-hour consultation
- Offers both injectable and oral tirzepatide options
- No membership fees and pricing decreases as treatment progresses
- Care from a board-certified family nurse practitioner
Where it loses points
- Compounded medications are not FDA-approved
- Available in only six states (NE, IA, SD, KS, CO, AZ)
- Cash-pay only; no insurance noted
- No named compounding pharmacy partner disclosed
- No LegitScript certification shown on site
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.