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Head-to-head · WeighScore

Synergy Rx vs Zera Health

Synergy Rx
Graded #41

Higher grade

vs+1.4000000000000057
Zera Health
Graded #61

Lower grade

The verdict

Synergy Rx takes it — 76.2/100 to 74.8/100, but only just.

Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact. Zera Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZera Health +18
62
80
Dose & formulationSynergy Rx +13
88
75
Clinical oversightSynergy Rx +10
92
82
Labs & monitoringSynergy Rx +13
66
53
FulfillmentZera Health +14
78
92
Contract termsSynergy Rx +13
68
55
Synergy Rx · left barZera Health · right bar

The numbers

MetricSynergy RxZera Health
WeighScore76.2/10074.8/100
GradeCC
Scorecard rank#41#61
SemaglutideFrom $199/mo$149/mo (compounded)
TirzepatideFrom $349/mo$199/mo (compounded)
CoverageNot disclosedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyYes
Synergy Rx

Graded #41 · C

Strengths

  • Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
  • Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
  • $100 welcome credit at checkout, and FSA/HSA eligible

Where it loses points

  • Publishes no GLP-1 price anywhere on its own site
  • At $349/mo tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves
  • No published cancellation or refund terms
Zera Health

Graded #61 · C

Strengths

  • Compounded semaglutide from $149/mo and tirzepatide from $199/mo, plus a $129/mo microdose option
  • Flat pricing — the same monthly cost at every dose as you titrate up
  • All-inclusive: medication, unlimited 24/7 provider messaging, and free shipping bundled in
  • Names its compounding pharmacy — Strive Pharmacy (licensed 503A)
  • Available in all 50 states with same-day approvals

Where it loses points

  • Operates as a technology platform, not the medical provider itself
  • Compounded GLP-1s are not FDA-approved (the site discloses this honestly)
  • Aggressive marketing results claims (e.g. '18% average', '93% kept it off') with 'results not typical' disclaimers
  • Legal entity name not published (footer shows only 'Zera Health')

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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