Head-to-head · WeighScore
Synergy Rx vs yourEra
The verdict
yourEra takes it — 83.8/100 to 76.2/100.
yourEra grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A both-molecule compounded program that publishes its prices up front — semaglutide $199/mo, tirzepatide $299/mo — across a 50-state clinician network, with an optional coaching-plus-labs membership and a NAD+/microdosing menu on the side.
We may earn a commission if you start care through some of these links, at no extra cost to you. Affiliate partners are listed first — a capped 3-point edge in board order only. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Synergy Rx | yourEra |
|---|---|---|
| WeighScore | 76.2/100 | 83.8/100 |
| Grade | C | B |
| Scorecard rank | #39 | #15 |
| Semaglutide | From $199/mo | $199/mo |
| Tirzepatide | From $349/mo | $299/mo |
| Coverage | Not disclosed | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #39 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Graded #15 · B
Strengths
- Transparent, publicly listed pricing — many compounded competitors hide price behind a quiz
- Both semaglutide and tirzepatide, not a single-drug menu, plus NAD+ and microdosing lines
- Markets a 50-state licensed-clinician network; no insurance required, HSA/FSA accepted
- Optional yourEra Optimum membership adds 1:1 coaching, a nutritionist, at-home lab draws and wearables
Where it loses points
- Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
- Mid-market pricing ($199 sema / $299 tirz) — above the cheapest compounders
- No brand-name lane and no oral route — weekly injectable only
- Thin independent footprint; the 50-state and efficacy claims are self-reported
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 43 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.