Head-to-head · WeighScore
Synergy Rx vs MadeMed
The verdict
MadeMed takes it — 80.4/100 to 76.2/100.
MadeMed grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Publishes its price at every single dose, so what a titrated dose costs is knowable on day one.
We may earn a commission if you start care through some of these links, at no extra cost to you. Affiliate partners are listed first — a capped 3-point edge in board order only. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Synergy Rx | MadeMed |
|---|---|---|
| WeighScore | 76.2/100 | 80.4/100 |
| Grade | C | B− |
| Scorecard rank | #39 | #29 |
| Semaglutide | From $199/mo | $239/mo quarterly (from $199/mo on 6 months) |
| Tirzepatide | From $349/mo | $399/mo quarterly (from $369/mo on 6 months) |
| Coverage | Not disclosed | 40 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #39 · C
Strengths
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- $100 welcome credit at checkout, and FSA/HSA eligible
Where it loses points
- Publishes no GLP-1 price anywhere on its own site
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
- No published cancellation or refund terms
Graded #29 · B−
Strengths
- One flat price at every dose, published dose by dose — semaglutide 0.25–2.4mg, tirzepatide 2.5–15mg
- LegitScript verified, with board-certified physician review and US compounding pharmacies
- Full refund minus a $39 visit fee if you are not prescribed, stated before checkout
- Oral semaglutide and oral tirzepatide alongside the injections; free overnight shipping with supplies
Where it loses points
- The most expensive tirzepatide here at $399/mo quarterly
- 40 states rather than nationwide
- No published recurring lab programme
- Ships one vial every two months, a less flexible cadence than a monthly refill
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 43 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.