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Head-to-head · WeighScore

SynergenX Health vs ZYP Medical

SynergenX Health
Graded #380

Lower grade

vs+16.199999999999996
ZYP Medical
Graded #66

Higher grade

The verdict

ZYP Medical takes it — 74.3/100 to 58.1/100.

ZYP Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZYP Medical +34
45
79
Dose & formulationZYP Medical +31
52
83
Clinical oversightZYP Medical +20
66
86
Labs & monitoringSynergenX Health +33
86
53
FulfillmentZYP Medical +11
55
66
Contract termsZYP Medical +14
47
61
SynergenX Health · left barZYP Medical · right bar

The numbers

MetricSynergenX HealthZYP Medical
WeighScore58.1/10074.3/100
GradeCC
Scorecard rank#380#66
Semaglutide$150/mo (starting dose, plus a separate fee, compounded)$150/mo
TirzepatideNot disclosed$233/mo
Coverage10 states6 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
SynergenX Health

Graded #380 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
ZYP Medical

Graded #66 · C

Strengths

  • Transparent flat-rate pricing including medication and shipping with no hidden fees
  • Low $50 initial one-hour consultation
  • Offers both injectable and oral tirzepatide options
  • No membership fees and pricing decreases as treatment progresses
  • Care from a board-certified family nurse practitioner

Where it loses points

  • Compounded medications are not FDA-approved
  • Available in only six states (NE, IA, SD, KS, CO, AZ)
  • Cash-pay only; no insurance noted
  • No named compounding pharmacy partner disclosed
  • No LegitScript certification shown on site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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