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Head-to-head · WeighScore

StackMD vs Tryozi

StackMD
Graded #259

Higher grade

vs+2
Tryozi
Graded #295

Lower grade

The verdict

StackMD takes it — 63.4/100 to 61.4/100, but only just.

StackMD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. StackMD is a New York telehealth platform (Medical 360 HC PLLC) selling compounded semaglutide and tirzepatide, both formulated with B12 and glycine, alongside NAD+, sermorelin and other longevity peptides. Tryozi is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueStackMD +1
46
45
Dose & formulationTryozi +10
54
64
Clinical oversightStackMD +4
78
74
Labs & monitoringStackMD +10
62
52
FulfillmentTryozi +1
89
90
Contract termsStackMD +20
69
49
StackMD · left barTryozi · right bar

The numbers

MetricStackMDTryozi
WeighScore63.4/10061.4/100
GradeCC
Scorecard rank#259#295
Semaglutide$125/mo (1 mg dose, plus a separate fee, compounded)$279/mo (compounded)
Tirzepatide$199/mo (5 mg dose, compounded)$379/mo (compounded)
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
StackMD

Graded #259 · C

Strengths

  • Publishes an exact price for every dose strength rather than a single 'from' figure — semaglutide $125-$225, tirzepatide $199-$449
  • Names both its legal entity (Medical 360 HC PLLC) and its prescribing telehealth partner, SamaritanMD
  • No membership or platform fee — the medication price is the whole price
  • States plainly that its compounded medications are 'not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality'
  • Telehealth offered in all 50 states per its terms, with free discreet shipping and FSA/HSA eligibility

Where it loses points

  • All sales are final — 'No refunds are issued except as described below', and dispensed medication cannot be returned
  • Compounding pharmacies are never named, only 'a licensed third-party pharmacy'
  • Price rises steeply with dose: tirzepatide runs $199 at 5mg to $449 at 30mg
  • Billing and refunds are handled by SamaritanMD — StackMD 'has no authority to issue refunds' on its behalf
  • Terms impose binding arbitration in New York and waive jury trial and class-action participation
Tryozi

Graded #295 · C

Strengths

  • Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
  • Price does not increase as your dose increases, stated plainly on the pricing page
  • Full total shown before payment, with the first-month discount and the ongoing rate both visible
  • States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
  • LegitScript certification verified against the issued seal, not just the badge

Where it loses points

  • Headline $139 is a first-month half-price offer; the ongoing rate is $279
  • Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
  • Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
  • No refund policy detail is published on the pricing page itself

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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