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Head-to-head · WeighScore

Spry vs SynergenX Health

Spry
Graded #409

Lower grade

vs+1.3000000000000043
SynergenX Health
Graded #380

Higher grade

The verdict

SynergenX Health takes it — 58.1/100 to 56.8/100, but only just.

SynergenX Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. SynergenX Health is a multi-state hormone and weight-loss clinic chain with 64 locations across 10 states offering a telehealth GLP-1 program currently available to Texas patients. Spry is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSpry +9
54
45
Dose & formulationSpry +12
64
52
Clinical oversightSynergenX Health +11
55
66
Labs & monitoringSynergenX Health +34
52
86
FulfillmentSpry +6
61
55
Contract termsSpry +8
55
47
Spry · left barSynergenX Health · right bar

The numbers

MetricSprySynergenX Health
WeighScore56.8/10058.1/100
GradeCC
Scorecard rank#409#380
Semaglutide$199/mo (starting dose, compounded)$150/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$299/mo (starting dose, compounded)Not disclosed
CoverageCoverage not published10 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Spry

Graded #409 · C

Strengths

  • Three named co-founders disclosed (Gabriel Mullins, Sara Yoder, Tyler Bowman) — better-than-average transparency
  • Pricing shown on the homepage ($199 semaglutide / $299 tirzepatide / $249–$299 peptides) — no full sign-up wall
  • Broader range (2 GLP-1s plus 3 anti-aging peptides) appeals to longevity buyers
  • No contracts or commitment required
  • LegitScript Certified with a public verification link

Where it loses points

  • Displays an "FDA Approved" badge though compounded GLP-1s are not FDA-approved finished drugs — potentially misleading
  • Intake reviewed by a nurse practitioner, not an MD
  • States served not disclosed publicly
  • Pharmacy partner not named, and 503A vs 503B designation not specified
  • FDA has issued this company a warning letter; the letter is public in FDA's warning-letter database
SynergenX Health

Graded #380 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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