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Head-to-head · WeighScore

SkyRx vs Wellspring Longevity Clinic

SkyRx
Graded #355

Higher grade

vs+5.5
Wellspring Longevity Clinic
Graded #467

Lower grade

The verdict

SkyRx takes it — 58.9/100 to 53.4/100.

SkyRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +11
56
45
Dose & formulationSkyRx +31
71
40
Clinical oversightWellspring Longevity Clinic +5
68
73
Labs & monitoringEven
52
52
FulfillmentSkyRx +3
64
61
Contract termsWellspring Longevity Clinic +35
20
55
SkyRx · left barWellspring Longevity Clinic · right bar

The numbers

MetricSkyRxWellspring Longevity Clinic
WeighScore58.9/10053.4/100
GradeCC
Scorecard rank#355#467
Semaglutide$199/mo (all doses, 12-month plan, compounded)Not disclosed
TirzepatideNot disclosedNot disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
SkyRx

Graded #355 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Strengths

  • Compounded GLP-1 (semaglutide) and GLP-1/GIP (tirzepatide) from a longevity-focused clinic
  • Also offers NAD+, peptide therapy, and GLP-1 microdosing
  • Transparent that medication is compounded by a licensed third-party pharmacy
  • Free carb and protein calculator tools on the site

Where it loses points

  • Pricing not published on the site — gated behind the intake
  • Euphemistic marketing ('Personalized GLP-1', 'appetite harmony') rather than naming semaglutide/tirzepatide plainly
  • Compounding pharmacy partner not named
  • Not LegitScript-certified; legal entity not named beyond the brand
  • States of operation not published

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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