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Head-to-head · WeighScore

SkyRx vs Vital Harmony Rx

SkyRx
Graded #355

Higher grade

vs+7.199999999999996
Vital Harmony Rx
Graded #484

Lower grade

The verdict

SkyRx takes it — 58.9/100 to 51.7/100.

SkyRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +11
56
45
Dose & formulationSkyRx +31
71
40
Clinical oversightSkyRx +3
68
65
Labs & monitoringSkyRx +2
52
50
FulfillmentSkyRx +1
64
63
Contract termsVital Harmony Rx +35
20
55
SkyRx · left barVital Harmony Rx · right bar

The numbers

MetricSkyRxVital Harmony Rx
WeighScore58.9/10051.7/100
GradeCC
Scorecard rank#355#484
Semaglutide$199/mo (all doses, 12-month plan, compounded)Not disclosed
TirzepatideNot disclosedNot disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
SkyRx

Graded #355 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed
Vital Harmony Rx

Graded #484 · C

Strengths

  • Verified LegitScript certification (ID 49230211) — a trust signal many compounded-GLP-1 DTC brands lack
  • Explicit compounded-medication + 'not a pharmacy/manufacturer' disclosure on-site
  • Both a semaglutide (GLP-1+B12) and a tirzepatide (GLP-1/GIP+B12) option
  • Operates on a named physician network (Beluga Health)

Where it loses points

  • NO pricing published anywhere on the site — a major gap for a cost-comparison directory; buyers cannot evaluate value without contacting the company
  • No specific state list (only 'entire country' claimed)
  • No named compounding pharmacy partner
  • No named medical director / PIC, no legal entity or governing law disclosed
  • Molecule strengths/dose tiers not published

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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