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Head-to-head · WeighScore

Silhouette MD vs Zeuss

Silhouette MD
Graded #123

Higher grade

vs+0.20000000000000284
Zeuss
Graded #132

Lower grade

The verdict

Silhouette MD takes it — 69.4/100 to 69.2/100, but only just.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan. Zeuss is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZeuss +11
74
85
Dose & formulationSilhouette MD +11
75
64
Clinical oversightSilhouette MD +5
77
72
Labs & monitoringSilhouette MD +2
54
52
FulfillmentEven
67
67
Contract termsZeuss +6
55
61
Silhouette MD · left barZeuss · right bar

The numbers

MetricSilhouette MDZeuss
WeighScore69.4/10069.2/100
GradeCC
Scorecard rank#123#132
Semaglutide$149/mo (compounded)$125/mo (compounded)
Tirzepatide$299/mo (compounded)$175/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Silhouette MD

Graded #123 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name
Zeuss

Graded #132 · C

Strengths

  • One-time-purchase model with no subscription — genuinely rare among DTC GLP-1 providers
  • Publishes the FDA compounded-medication disclaimer
  • Names both 503A and 503B compounding pathways — uncommon transparency
  • Bundled pricing covers provider review, meds, and cold-chain shipping with no hidden fees
  • Full refund if a physician can't prescribe

Where it loses points

  • 503A pharmacy partner not named (only generic '503A and 503B state-licensed' framing)
  • LegitScript certification not mentioned
  • No named medical director or physician leadership
  • Full states-served list not disclosed
  • Corporate legal entity not disclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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