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Head-to-head · WeighScore

Silhouette MD vs Trimrose

Silhouette MD
Graded #123

Higher grade

vs+14.000000000000007
Trimrose
Graded #440

Lower grade

The verdict

Silhouette MD takes it — 69.4/100 to 55.4/100.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSilhouette MD +34
74
40
Dose & formulationSilhouette MD +11
75
64
Clinical oversightSilhouette MD +9
77
68
Labs & monitoringSilhouette MD +2
54
52
FulfillmentSilhouette MD +10
67
57
Contract termsEven
55
55
Silhouette MD · left barTrimrose · right bar

The numbers

MetricSilhouette MDTrimrose
WeighScore69.4/10055.4/100
GradeCC
Scorecard rank#123#440
Semaglutide$149/mo (compounded)Not disclosed
Tirzepatide$299/mo (compounded)Not disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
Silhouette MD

Graded #123 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name
Trimrose

Graded #440 · C

Strengths

  • Free, no-cost, no-obligation online eligibility quiz before any commitment
  • Offers a choice of a weekly compounded GLP-1 injection or a daily oral option
  • Fully online — assessment, provider review, and home delivery with ongoing support

Where it loses points

  • Runs on the CareValidate white-label platform and isn't the medical provider itself — a support@carevalidate.com address is exposed on the site
  • Pricing isn't shown publicly; the cost and the specific compounded molecule appear only after you complete the eligibility quiz
  • The states served, pharmacy partner and any LegitScript/503A certification aren't disclosed on the public site
  • Markets 'up to 22.5% of body weight' — a trial figure for branded tirzepatide, not a guaranteed or compounded-specific outcome
  • Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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