Head-to-head · WeighScore
Silhouette MD vs Trillium Meds
The verdict
Too close to call — both grade 69.4/100 (C).
Silhouette MD and Trillium Meds land on the same WeighScore, so neither clears the other on our six graded dimensions. Silhouette MD sits one line higher on the board (#129 vs #130) on the underlying tiebreak, but it's a genuine coin-flip — pick on the factors and prices that matter most to you below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Silhouette MD | Trillium Meds |
|---|---|---|
| WeighScore | 69.4/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #129 | #130 |
| Semaglutide | $149/mo (compounded) | $119/mo (3-month plan, compounded) |
| Tirzepatide | $299/mo (compounded) | $199/mo (3-month plan, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #129 · C
Strengths
- Compounded semaglutide and tirzepatide in both injectable and oral formulations
- Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
- Transparent, published pricing starting at $149/mo for semaglutide injection
- Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health
Where it loses points
- Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
- State availability not published
- Newer brand with limited independent review history
- Medications are compounded, not FDA-approved brand-name
Graded #130 · C
Strengths
- LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
- All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
- Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
- Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
- Klarna and Affirm financing available; pause anytime with no long-term commitment required
Where it loses points
- No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
- Small single-operator platform may limit capacity and support consistency as patient volume grows
- Compounded medications are not FDA-approved; newer platform with limited long-term public track record
- Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
- No live video consult disclosed; async intake-form-based provider review by external licensed provider network
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.