Head-to-head · WeighScore
Sesame Care vs Vyora Wellness
The verdict
Sesame Care takes it — 87.8/100 to 60.5/100.
Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Sesame Care | Vyora Wellness |
|---|---|---|
| WeighScore | 87.8/100 | 60.5/100 |
| Grade | B+ | C |
| Scorecard rank | #2 | #322 |
| Semaglutide | From $149/mo (brand Wegovy pill) | $299/mo (compounded) |
| Tirzepatide | Brand Zepbound (price varies) | $399/mo (compounded) |
| Coverage | Nationwide marketplace | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #2 · B+
Strengths
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
- Oral routes available (Wegovy pill, Rybelsus)
Where it loses points
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Graded #322 · C
Strengths
- LegitScript certified
- Price includes nutritional guidance, 24/7 coaching, and community access
- Both semaglutide and tirzepatide available
- BMI 25+ eligibility threshold (lower than some competitors)
Where it loses points
- State availability not publicly disclosed
- Pricing is above average ($299–$399/mo) compared to competitors
- Compounded only — no brand-name options
- Broader platform (metabolic, longevity, topical products)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.