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Head-to-head · WeighScore

Semaglutide Online vs Trillium Meds

Semaglutide Online
Graded #64

Higher grade

vs+4.8999999999999915
Trillium Meds
Graded #124

Lower grade

The verdict

Semaglutide Online takes it — 74.3/100 to 69.4/100.

Semaglutide Online grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Semaglutide Online is a LegitScript-certified telehealth platform prescribing compounded and brand-name GLP-1/GIP medications nationwide (excluding Alabama).

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueTrillium Meds +4
66
70
Dose & formulationSemaglutide Online +32
96
64
Clinical oversightTrillium Meds +3
81
84
Labs & monitoringTrillium Meds +23
52
75
FulfillmentSemaglutide Online +6
85
79
Contract termsSemaglutide Online +35
55
20
Semaglutide Online · left barTrillium Meds · right bar

The numbers

MetricSemaglutide OnlineTrillium Meds
WeighScore74.3/10069.4/100
GradeCC
Scorecard rank#64#124
Semaglutide$199/mo (all doses, compounded)$119/mo (3-month plan, compounded)
Tirzepatide$299/mo (all doses, compounded)$199/mo (3-month plan, compounded)
CoverageAll 50 statesAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
Semaglutide Online

Graded #64 · C

Strengths

  • LegitScript certified — passes accreditation standards recognized by Google and Visa for online telehealth
  • Compounded all-in pricing: semaglutide $199/mo and tirzepatide $299/mo includes medication, provider care, and shipping
  • Brand-name options (Wegovy pill, injectable sema, Zepbound) available for eligible patients, potentially $0-$25/mo with insurance
  • Nationwide (49 states + DC); no appointment required, licensed provider reviews intake within 12 hours
  • 0% financing through Credee from $79/month (12-24 months) plus Affirm and Klarna with ~97% approval rate

Where it loses points

  • No labs or clinical monitoring disclosed — blood work requirements not mentioned anywhere on site
  • Leadership team and medical director not identified on site — no named prescribers or company founders published
  • Brand-name prescriptions add a $44/month provider fee on top of medication cost, raising total price to $193-$343/mo
  • No coaching, dietitian, or behavioral support at any tier — medication and async provider access only
  • 30-day satisfaction guarantee covers evaluation fee only; medication costs explicitly non-refundable
Trillium Meds

Graded #124 · C

Strengths

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

Where it loses points

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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