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Head-to-head · WeighScore

Semaglutide Online vs SynergenX Health

Semaglutide Online
Graded #64

Higher grade

vs+15.899999999999999
SynergenX Health
Graded #374

Lower grade

The verdict

Semaglutide Online takes it — 74.3/100 to 58.4/100.

Semaglutide Online grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Semaglutide Online is a LegitScript-certified telehealth platform prescribing compounded and brand-name GLP-1/GIP medications nationwide (excluding Alabama).

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSemaglutide Online +20
66
46
Dose & formulationSemaglutide Online +44
96
52
Clinical oversightSemaglutide Online +15
81
66
Labs & monitoringSynergenX Health +34
52
86
FulfillmentSemaglutide Online +30
85
55
Contract termsSemaglutide Online +8
55
47
Semaglutide Online · left barSynergenX Health · right bar

The numbers

MetricSemaglutide OnlineSynergenX Health
WeighScore74.3/10058.4/100
GradeCC
Scorecard rank#64#374
Semaglutide$199/mo (all doses, compounded)$150/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$299/mo (all doses, compounded)Not disclosed
CoverageAll 50 states10 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
Semaglutide Online

Graded #64 · C

Strengths

  • LegitScript certified — passes accreditation standards recognized by Google and Visa for online telehealth
  • Compounded all-in pricing: semaglutide $199/mo and tirzepatide $299/mo includes medication, provider care, and shipping
  • Brand-name options (Wegovy pill, injectable sema, Zepbound) available for eligible patients, potentially $0-$25/mo with insurance
  • Nationwide (49 states + DC); no appointment required, licensed provider reviews intake within 12 hours
  • 0% financing through Credee from $79/month (12-24 months) plus Affirm and Klarna with ~97% approval rate

Where it loses points

  • No labs or clinical monitoring disclosed — blood work requirements not mentioned anywhere on site
  • Leadership team and medical director not identified on site — no named prescribers or company founders published
  • Brand-name prescriptions add a $44/month provider fee on top of medication cost, raising total price to $193-$343/mo
  • No coaching, dietitian, or behavioral support at any tier — medication and async provider access only
  • 30-day satisfaction guarantee covers evaluation fee only; medication costs explicitly non-refundable
SynergenX Health

Graded #374 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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