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Head-to-head · WeighScore

Rylo Health vs VyrarX

Rylo Health
Graded #236

Lower grade

vs+3.8999999999999915
VyrarX
Graded #145

Higher grade

The verdict

VyrarX takes it — 68.6/100 to 64.7/100.

VyrarX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. VyrarX is a LegitScript-certified telehealth platform offering compounded semaglutide (from $179/month) and compounded tirzepatide (from $329/month) via weekly injection, prescribed by licensed US physicians.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRylo Health +3
64
61
Dose & formulationEven
64
64
Clinical oversightVyrarX +9
75
84
Labs & monitoringVyrarX +19
53
72
FulfillmentRylo Health +12
83
71
Contract termsVyrarX +18
37
55
Rylo Health · left barVyrarX · right bar

The numbers

MetricRylo HealthVyrarX
WeighScore64.7/10068.6/100
GradeCC
Scorecard rank#236#145
Semaglutide$149/mo (promotional rate, compounded)$179/mo (starting dose, compounded)
Tirzepatide$249/mo (compounded)$329/mo (starting dose, compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Rylo Health

Graded #236 · C

Strengths

  • Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
  • Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
  • Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
  • Cancel in one click from the patient portal, with no contracts and no cancellation fees
  • Peptide line priced openly, including NAD+ and sermorelin

Where it loses points

  • Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
  • No LegitScript certification is claimed or displayed
  • Several peptide products are advertised as coming soon rather than available
  • No published refund policy beyond the no-cancellation-fee statement
VyrarX

Graded #145 · C

Strengths

  • LegitScript certified with active seal (ID 51177727)
  • Semaglutide starting at $179/month with free shipping included
  • 1:1 direct provider messaging and personalized titration plan in every plan
  • Nutrition coaching included with the weight-loss program
  • Provider review completed within 24 hours; no insurance required

Where it loses points

  • Tirzepatide at $329/month starting is at the high end of the compounded market
  • Compounding pharmacy not named on any public page
  • No physician names or clinical leadership disclosed publicly
  • Only 47 states covered — the 3 excluded states are not named on the site
  • Labs not included in the weight-loss plan

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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