Head-to-head · WeighScore
Rylo Health vs Trillium Meds
The verdict
Trillium Meds takes it — 69.4/100 to 64.7/100.
Trillium Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Rylo Health | Trillium Meds |
|---|---|---|
| WeighScore | 64.7/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #240 | #130 |
| Semaglutide | $149/mo (promotional rate, compounded) | $119/mo (3-month plan, compounded) |
| Tirzepatide | $249/mo (compounded) | $199/mo (3-month plan, compounded) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #240 · C
Strengths
- Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
- Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
- Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
- Cancel in one click from the patient portal, with no contracts and no cancellation fees
- Peptide line priced openly, including NAD+ and sermorelin
Where it loses points
- Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
- No LegitScript certification is claimed or displayed
- Several peptide products are advertised as coming soon rather than available
- No published refund policy beyond the no-cancellation-fee statement
Graded #130 · C
Strengths
- LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
- All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
- Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
- Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
- Klarna and Affirm financing available; pause anytime with no long-term commitment required
Where it loses points
- No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
- Small single-operator platform may limit capacity and support consistency as patient volume grows
- Compounded medications are not FDA-approved; newer platform with limited long-term public track record
- Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
- No live video consult disclosed; async intake-form-based provider review by external licensed provider network
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.