Head-to-head · WeighScore
RxSpan MD vs ZYP Medical
The verdict
RxSpan MD takes it — 86.8/100 to 74.3/100.
RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | RxSpan MD | ZYP Medical |
|---|---|---|
| WeighScore | 86.8/100 | 74.3/100 |
| Grade | B | C |
| Scorecard rank | #4 | #66 |
| Semaglutide | From $194/mo | $150/mo |
| Tirzepatide | $329/mo | $233/mo |
| Coverage | All 50 states | 6 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #4 · B
Strengths
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
- Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching
Where it loses points
- Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
- Published pricing is for the compounded line — brand-name pricing isn’t itemized
- A prescription isn’t guaranteed — a provider reviews eligibility after checkout
Graded #66 · C
Strengths
- Transparent flat-rate pricing including medication and shipping with no hidden fees
- Low $50 initial one-hour consultation
- Offers both injectable and oral tirzepatide options
- No membership fees and pricing decreases as treatment progresses
- Care from a board-certified family nurse practitioner
Where it loses points
- Compounded medications are not FDA-approved
- Available in only six states (NE, IA, SD, KS, CO, AZ)
- Cash-pay only; no insurance noted
- No named compounding pharmacy partner disclosed
- No LegitScript certification shown on site
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.