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Head-to-head · WeighScore

Rex MD vs SynergenX Health

Rex MD
Graded #112

Higher grade

vs+12.100000000000001
SynergenX Health
Graded #380

Lower grade

The verdict

Rex MD takes it — 70.2/100 to 58.1/100.

Rex MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Rex MD is a US-based men's-health telehealth platform (a LifeMD brand) offering a 100 percent online GLP-1 weight-management program.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRex MD +15
60
45
Dose & formulationRex MD +25
77
52
Clinical oversightRex MD +18
84
66
Labs & monitoringSynergenX Health +33
53
86
FulfillmentRex MD +34
89
55
Contract termsRex MD +8
55
47
Rex MD · left barSynergenX Health · right bar

The numbers

MetricRex MDSynergenX Health
WeighScore70.2/10058.1/100
GradeCC
Scorecard rank#112#380
Semaglutide$199/mo (brand-name)$150/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$349/mo (brand Zepbound)Not disclosed
CoverageAll 50 states10 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Rex MD

Graded #112 · C

Strengths

  • Flat $199/mo program bundles consult, medication and overnight shipping
  • Brand-name semaglutide and Zepbound vials, not just compounded
  • Serves all 50 states, fully online
  • LegitScript certified with US-based, state-licensed providers
  • Backed by parent company LifeMD

Where it loses points

  • Does not accept insurance
  • Marketed primarily to men via a men's-health platform
  • Zepbound vial cost rises with dose titration
  • Branded-only program costs more than compounded options
SynergenX Health

Graded #380 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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