Head-to-head · WeighScore
Primary Clinic (Direct GLP) vs SynergenX Health
The verdict
Primary Clinic (Direct GLP) takes it — 68.7/100 to 58.1/100.
Primary Clinic (Direct GLP) grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Primary Clinic (Direct GLP) is a Direct Primary Care membership rather than the usual direct-to-consumer GLP-1 marketplace.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Primary Clinic (Direct GLP) | SynergenX Health |
|---|---|---|
| WeighScore | 68.7/100 | 58.1/100 |
| Grade | C | C |
| Scorecard rank | #145 | #380 |
| Semaglutide | $65/mo (0.25 mg dose, promotional rate, compounded) | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | $110/mo (2.5 mg dose, promotional rate, compounded) | Not disclosed |
| Coverage | 10 states | 10 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #145 · C
Strengths
- Direct Primary Care model integrates GLP-1 with continuous primary care — unlike most direct-to-consumer platforms
- GLP-1 at wholesale cost with no markup — semaglutide from $65/mo, tirzepatide from $110/mo (members only)
- Unlimited primary care visits, direct text access, and same-day care bundled in the $89/mo membership
- Routine labs and thousands of medications included in membership — no surprise bills
- Per-dose pricing shown publicly for all 8 dose tiers of both semaglutide and tirzepatide
Where it loses points
- 10 states only (WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA) — limited vs 50-state platforms
- Membership required to access wholesale pricing — $89/mo adds ~$1,068/yr in fixed cost
- 503A pharmacy partners not named
- LegitScript certification not mentioned on the site
- Medical director and corporate legal entity not disclosed
Graded #380 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.