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Head-to-head · WeighScore

Primary Clinic (Direct GLP) vs Silhouette MD

Primary Clinic (Direct GLP)
Graded #145

Lower grade

vs+0.7000000000000028
Silhouette MD
Graded #131

Higher grade

The verdict

Silhouette MD takes it — 69.4/100 to 68.7/100, but only just.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan. Primary Clinic (Direct GLP) is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePrimary Clinic (Direct GLP) +4
78
74
Dose & formulationSilhouette MD +21
54
75
Clinical oversightSilhouette MD +2
75
77
Labs & monitoringPrimary Clinic (Direct GLP) +22
76
54
FulfillmentPrimary Clinic (Direct GLP) +6
73
67
Contract termsSilhouette MD +14
41
55
Primary Clinic (Direct GLP) · left barSilhouette MD · right bar

The numbers

MetricPrimary Clinic (Direct GLP)Silhouette MD
WeighScore68.7/10069.4/100
GradeCC
Scorecard rank#145#131
Semaglutide$65/mo (0.25 mg dose, promotional rate, compounded)$149/mo (compounded)
Tirzepatide$110/mo (2.5 mg dose, promotional rate, compounded)$299/mo (compounded)
Coverage10 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes

Strengths

  • Direct Primary Care model integrates GLP-1 with continuous primary care — unlike most direct-to-consumer platforms
  • GLP-1 at wholesale cost with no markup — semaglutide from $65/mo, tirzepatide from $110/mo (members only)
  • Unlimited primary care visits, direct text access, and same-day care bundled in the $89/mo membership
  • Routine labs and thousands of medications included in membership — no surprise bills
  • Per-dose pricing shown publicly for all 8 dose tiers of both semaglutide and tirzepatide

Where it loses points

  • 10 states only (WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA) — limited vs 50-state platforms
  • Membership required to access wholesale pricing — $89/mo adds ~$1,068/yr in fixed cost
  • 503A pharmacy partners not named
  • LegitScript certification not mentioned on the site
  • Medical director and corporate legal entity not disclosed
Silhouette MD

Graded #131 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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