Head-to-head · WeighScore
PlushCare vs VyrarX
The verdict
PlushCare takes it — 74.5/100 to 68.6/100.
PlushCare grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Established virtual primary-care telehealth platform (subsidiary of Transcarent, Inc., a Delaware corporation, alongside Accolade, 2nd.MD, and 98point6 by Transcarent).
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | PlushCare | VyrarX |
|---|---|---|
| WeighScore | 74.5/100 | 68.6/100 |
| Grade | C | C |
| Scorecard rank | #63 | #145 |
| Semaglutide | $149/mo (starting dose, compounded) | $179/mo (starting dose, compounded) |
| Tirzepatide | $399/mo (starting dose, compounded) | $329/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #63 · C
Strengths
- Available in all 50 states
- Appointments with US board-certified physicians, not nurse practitioners only
- Virtual primary care — the same doctor can manage GLP-1s alongside other health needs
- Owned by Transcarent, a venture-backed health platform with a named corporate parent
Where it loses points
- Facing a California class action alleging deceptive subscription enrollment and unauthorized charges after cancellation
- GLP-1 prescribing is up to the clinician at the visit — not guaranteed at signup
- BBB complaints center on the membership cancellation process
Graded #145 · C
Strengths
- LegitScript certified with active seal (ID 51177727)
- Semaglutide starting at $179/month with free shipping included
- 1:1 direct provider messaging and personalized titration plan in every plan
- Nutrition coaching included with the weight-loss program
- Provider review completed within 24 hours; no insurance required
Where it loses points
- Tirzepatide at $329/month starting is at the high end of the compounded market
- Compounding pharmacy not named on any public page
- No physician names or clinical leadership disclosed publicly
- Only 47 states covered — the 3 excluded states are not named on the site
- Labs not included in the weight-loss plan
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.