Head-to-head · WeighScore
PlexusDx vs Wholesome Clinic
The verdict
Wholesome Clinic takes it — 79.6/100 to 67.7/100.
Wholesome Clinic grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | PlexusDx | Wholesome Clinic |
|---|---|---|
| WeighScore | 67.7/100 | 79.6/100 |
| Grade | C | C+ |
| Scorecard rank | #158 | #40 |
| Semaglutide | $149/mo (starting dose, compounded) | $149/mo (starting dose, compounded) |
| Tirzepatide | $249/mo (starting dose, compounded) | $349/mo (starting dose, compounded) |
| Coverage | All 50 states | 7 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #158 · C
Strengths
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
Where it loses points
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Graded #40 · C+
Strengths
- Publishes standing per-dose self-pay prices for compounded semaglutide and tirzepatide, oral and injectable
- Compounded semaglutide from $109/mo (oral) or $149/mo (injectable); brand Wegovy/Zepbound offered when appropriate
- Telehealth across seven states plus an in-person option at its Frisco, TX office
Where it loses points
- $149 initial evaluation and $75 follow-up visits are billed separately from medication
- Filled through your 'preferred pharmacy' — no single named compounding pharmacy partner
- No LegitScript certification displayed
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.