Head-to-head · WeighScore
PlexusDx vs Tryozi
The verdict
PlexusDx takes it — 67.7/100 to 61.4/100.
PlexusDx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | PlexusDx | Tryozi |
|---|---|---|
| WeighScore | 67.7/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #158 | #294 |
| Semaglutide | $149/mo (starting dose, compounded) | $279/mo (compounded) |
| Tirzepatide | $249/mo (starting dose, compounded) | $379/mo (compounded) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #158 · C
Strengths
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
Where it loses points
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Graded #294 · C
Strengths
- Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
- Price does not increase as your dose increases, stated plainly on the pricing page
- Full total shown before payment, with the first-month discount and the ongoing rate both visible
- States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
- LegitScript certification verified against the issued seal, not just the badge
Where it loses points
- Headline $139 is a first-month half-price offer; the ongoing rate is $279
- Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
- Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
- No refund policy detail is published on the pricing page itself
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.