Head-to-head · WeighScore
PlexusDx vs Trimi
The verdict
Trimi takes it — 86.4/100 to 67.7/100.
Trimi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Bottom-quartile pricing on both molecules under one flat membership, shipped free nationwide — a strong-value pick sitting just behind the top tier.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | PlexusDx | Trimi |
|---|---|---|
| WeighScore | 67.7/100 | 86.4/100 |
| Grade | C | B |
| Scorecard rank | #158 | #7 |
| Semaglutide | $149/mo (starting dose, compounded) | $129/mo |
| Tirzepatide | $249/mo (starting dose, compounded) | $199/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #158 · C
Strengths
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
Where it loses points
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Graded #7 · B
Strengths
- Low flat pricing on both semaglutide and tirzepatide
- Both molecules on a single membership
- Free shipping to all 50 states
- Fast dispatch once the prescriber signs off
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- Injection only — no oral or sublingual route
- Dispensing pharmacy not publicly named
- Shorter public track record than the incumbents
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.