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Head-to-head · WeighScore

PlexusDx vs Rex MD

PlexusDx
Graded #162

Lower grade

vs+2.5
Rex MD
Graded #112

Higher grade

The verdict

Rex MD takes it — 70.2/100 to 67.7/100.

Rex MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Rex MD is a US-based men's-health telehealth platform (a LifeMD brand) offering a 100 percent online GLP-1 weight-management program.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePlexusDx +14
74
60
Dose & formulationRex MD +13
64
77
Clinical oversightRex MD +10
74
84
Labs & monitoringRex MD +1
52
53
FulfillmentRex MD +11
78
89
Contract termsEven
55
55
PlexusDx · left barRex MD · right bar

The numbers

MetricPlexusDxRex MD
WeighScore67.7/10070.2/100
GradeCC
Scorecard rank#162#112
Semaglutide$149/mo (starting dose, compounded)$199/mo (brand-name)
Tirzepatide$249/mo (starting dose, compounded)$349/mo (brand Zepbound)
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
PlexusDx

Graded #162 · C

Strengths

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Where it loses points

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted
Rex MD

Graded #112 · C

Strengths

  • Flat $199/mo program bundles consult, medication and overnight shipping
  • Brand-name semaglutide and Zepbound vials, not just compounded
  • Serves all 50 states, fully online
  • LegitScript certified with US-based, state-licensed providers
  • Backed by parent company LifeMD

Where it loses points

  • Does not accept insurance
  • Marketed primarily to men via a men's-health platform
  • Zepbound vial cost rises with dose titration
  • Branded-only program costs more than compounded options

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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