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Head-to-head · WeighScore

PlexusDx vs PlushCare

PlexusDx
Graded #162

Lower grade

vs+6.799999999999997
PlushCare
Graded #64

Higher grade

The verdict

PlushCare takes it — 74.5/100 to 67.7/100.

PlushCare grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Established virtual primary-care telehealth platform (subsidiary of Transcarent, Inc., a Delaware corporation, alongside Accolade, 2nd.MD, and 98point6 by Transcarent).

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
74
74
Dose & formulationPlushCare +13
64
77
Clinical oversightPlushCare +8
74
82
Labs & monitoringPlushCare +25
52
77
FulfillmentEven
78
78
Contract termsPlexusDx +14
55
41
PlexusDx · left barPlushCare · right bar

The numbers

MetricPlexusDxPlushCare
WeighScore67.7/10074.5/100
GradeCC
Scorecard rank#162#64
Semaglutide$149/mo (starting dose, compounded)$149/mo (starting dose, compounded)
Tirzepatide$249/mo (starting dose, compounded)$399/mo (starting dose, compounded)
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
PlexusDx

Graded #162 · C

Strengths

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Where it loses points

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted
PlushCare

Graded #64 · C

Strengths

  • Available in all 50 states
  • Appointments with US board-certified physicians, not nurse practitioners only
  • Virtual primary care — the same doctor can manage GLP-1s alongside other health needs
  • Owned by Transcarent, a venture-backed health platform with a named corporate parent

Where it loses points

  • Facing a California class action alleging deceptive subscription enrollment and unauthorized charges after cancellation
  • GLP-1 prescribing is up to the clinician at the visit — not guaranteed at signup
  • BBB complaints center on the membership cancellation process

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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