Head-to-head · WeighScore
Piper vs PlexusDx
The verdict
Piper takes it — 81.9/100 to 67.7/100.
Piper grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mid-value both-molecule pricing ($135/$199), nationwide, though not verified.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Piper | PlexusDx |
|---|---|---|
| WeighScore | 81.9/100 | 67.7/100 |
| Grade | B− | C |
| Scorecard rank | #34 | #158 |
| Semaglutide | $135/mo | $149/mo (starting dose, compounded) |
| Tirzepatide | $199/mo | $249/mo (starting dose, compounded) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #34 · B−
Strengths
- $135 sema / $199 tirz
- All 50 states
- Both molecules
Where it loses points
- Not LegitScript-verified
- Injection-only
- Monitoring detail limited
Graded #158 · C
Strengths
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
Where it loses points
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.