Head-to-head · WeighScore
Peptivo vs Silhouette MD
The verdict
Silhouette MD takes it — 69.4/100 to 60.1/100.
Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Peptivo | Silhouette MD |
|---|---|---|
| WeighScore | 60.1/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #331 | #129 |
| Semaglutide | Not disclosed | $149/mo (compounded) |
| Tirzepatide | Not disclosed | $299/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #331 · C
Strengths
- Low entry pricing — GLP-1 weight-loss plans starting at $169/mo, with free discreet shipping
- Same-day provider visits and 24/7 provider messaging; 100% online
- Compounded in the USA at FDA-registered labs; can also prescribe brand GLP-1 (Ozempic, Wegovy, Zepbound)
- FSA/HSA eligible with upfront pricing
Where it loses points
- GLP-1 products use generic names ('GLP-1 Daily Support', 'Weight Loss Boost') — semaglutide/tirzepatide not clearly broken out
- Compounding pharmacy/lab partner not named
- Limited published policies (privacy and terms only; no HIPAA notice or refund policy found)
- Not LegitScript-certified (no certification displayed)
Graded #129 · C
Strengths
- Compounded semaglutide and tirzepatide in both injectable and oral formulations
- Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
- Transparent, published pricing starting at $149/mo for semaglutide injection
- Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health
Where it loses points
- Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
- State availability not published
- Newer brand with limited independent review history
- Medications are compounded, not FDA-approved brand-name
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.