Head-to-head · WeighScore
PeptidesRx vs Silhouette MD
The verdict
Silhouette MD takes it — 69.4/100 to 64.1/100.
Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | PeptidesRx | Silhouette MD |
|---|---|---|
| WeighScore | 64.1/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #247 | #131 |
| Semaglutide | $169/mo (0.25 mg dose, compounded) | $149/mo (compounded) |
| Tirzepatide | $309/mo (2.5 mg dose, compounded) | $299/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #247 · C
Strengths
- Compliance-focused positioning vs gray-market vendors
- Board-certified medical director
- Transparent pricing with no surprise fees
- Real prescriptions, not research-chemical channel
Where it loses points
- Smaller scale than Henry Meds or Hims
- Wide peptide menu may distract from GLP-1 focus
Graded #131 · C
Strengths
- Compounded semaglutide and tirzepatide in both injectable and oral formulations
- Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
- Transparent, published pricing starting at $149/mo for semaglutide injection
- Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health
Where it loses points
- Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
- State availability not published
- Newer brand with limited independent review history
- Medications are compounded, not FDA-approved brand-name
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.