Head-to-head · WeighScore
PCOS Sisters vs Vyora Wellness
The verdict
PCOS Sisters takes it — 66/100 to 60.5/100.
PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | PCOS Sisters | Vyora Wellness |
|---|---|---|
| WeighScore | 66/100 | 60.5/100 |
| Grade | C | C |
| Scorecard rank | #211 | #321 |
| Semaglutide | $150/mo (plus a separate fee, compounded) | $299/mo (compounded) |
| Tirzepatide | $150/mo (plus a separate fee, compounded) | $399/mo (compounded) |
| Coverage | 12 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #211 · C
Strengths
- Dedicated PCOS specialty model with metabolic program and fitness app included
- Transparent 150 dollars per month GLP-1 management fee
- Names real partner pharmacies (Strive, Striker) and lists phone support
Where it loses points
- Only 12 states served
- Membership required on top of the medical program
- Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Graded #321 · C
Strengths
- LegitScript certified
- Price includes nutritional guidance, 24/7 coaching, and community access
- Both semaglutide and tirzepatide available
- BMI 25+ eligibility threshold (lower than some competitors)
Where it loses points
- State availability not publicly disclosed
- Pricing is above average ($299–$399/mo) compared to competitors
- Compounded only — no brand-name options
- Broader platform (metabolic, longevity, topical products)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.