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Head-to-head · WeighScore

PCOS Sisters vs Tru2u

PCOS Sisters
Graded #219

Higher grade

vs+1.2999999999999972
Tru2u
Graded #245

Lower grade

The verdict

PCOS Sisters takes it — 65.7/100 to 64.4/100, but only just.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required. Tru2u is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +5
61
56
Dose & formulationPCOS Sisters +5
88
83
Clinical oversightPCOS Sisters +2
70
68
Labs & monitoringPCOS Sisters +1
52
51
FulfillmentTru2u +3
65
68
Contract termsTru2u +14
41
55
PCOS Sisters · left barTru2u · right bar

The numbers

MetricPCOS SistersTru2u
WeighScore65.7/10064.4/100
GradeCC
Scorecard rank#219#245
Semaglutide$150/mo (plus a separate fee, compounded)$225/mo
Tirzepatide$150/mo (plus a separate fee, compounded)$345/mo
Coverage12 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesYes
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Tru2u

Graded #245 · C

Strengths

  • Offers compounded semaglutide and tirzepatide plus a combined GLP Squared injection
  • Both injectable and oral GLP-1 tablet options available
  • Transparent upfront monthly pricing with free shipping

Where it loses points

  • No compounding pharmacy publicly named and no LegitScript seal shown
  • Tirzepatide at 345 dollars per month is higher than many compounded competitors
  • States served are not published; site states US-only availability

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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