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Head-to-head · WeighScore

PCOS Sisters vs Trimrose

PCOS Sisters
Graded #219

Higher grade

vs+10.5
Trimrose
Graded #446

Lower grade

The verdict

PCOS Sisters takes it — 65.7/100 to 55.2/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +22
61
39
Dose & formulationPCOS Sisters +24
88
64
Clinical oversightPCOS Sisters +2
70
68
Labs & monitoringEven
52
52
FulfillmentPCOS Sisters +8
65
57
Contract termsTrimrose +14
41
55
PCOS Sisters · left barTrimrose · right bar

The numbers

MetricPCOS SistersTrimrose
WeighScore65.7/10055.2/100
GradeCC
Scorecard rank#219#446
Semaglutide$150/mo (plus a separate fee, compounded)Not disclosed
Tirzepatide$150/mo (plus a separate fee, compounded)Not disclosed
Coverage12 statesCoverage not published
Brand-name accessYesYes
Oral / sublingualYesYes
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Trimrose

Graded #446 · C

Strengths

  • Free, no-cost, no-obligation online eligibility quiz before any commitment
  • Offers a choice of a weekly compounded GLP-1 injection or a daily oral option
  • Fully online — assessment, provider review, and home delivery with ongoing support

Where it loses points

  • Runs on the CareValidate white-label platform and isn't the medical provider itself — a support@carevalidate.com address is exposed on the site
  • Pricing isn't shown publicly; the cost and the specific compounded molecule appear only after you complete the eligibility quiz
  • The states served, pharmacy partner and any LegitScript/503A certification aren't disclosed on the public site
  • Markets 'up to 22.5% of body weight' — a trial figure for branded tirzepatide, not a guaranteed or compounded-specific outcome
  • Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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