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Head-to-head · WeighScore

PCOS Sisters vs Silhouette MD

PCOS Sisters
Graded #218

Lower grade

vs+3.700000000000003
Silhouette MD
Graded #129

Higher grade

The verdict

Silhouette MD takes it — 69.4/100 to 65.7/100.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSilhouette MD +13
61
74
Dose & formulationPCOS Sisters +13
88
75
Clinical oversightSilhouette MD +7
70
77
Labs & monitoringSilhouette MD +2
52
54
FulfillmentSilhouette MD +2
65
67
Contract termsSilhouette MD +14
41
55
PCOS Sisters · left barSilhouette MD · right bar

The numbers

MetricPCOS SistersSilhouette MD
WeighScore65.7/10069.4/100
GradeCC
Scorecard rank#218#129
Semaglutide$150/mo (plus a separate fee, compounded)$149/mo (compounded)
Tirzepatide$150/mo (plus a separate fee, compounded)$299/mo (compounded)
Coverage12 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesYes
PCOS Sisters

Graded #218 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Silhouette MD

Graded #129 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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