Head-to-head · WeighScore
Optimized Health vs VyrarX
The verdict
VyrarX takes it — 68.6/100 to 67.2/100, but only just.
VyrarX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. VyrarX is a LegitScript-certified telehealth platform offering compounded semaglutide (from $179/month) and compounded tirzepatide (from $329/month) via weekly injection, prescribed by licensed US physicians. Optimized Health is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Optimized Health | VyrarX |
|---|---|---|
| WeighScore | 67.2/100 | 68.6/100 |
| Grade | C | C |
| Scorecard rank | #166 | #145 |
| Semaglutide | $200/mo (starting dose, compounded) | $179/mo (starting dose, compounded) |
| Tirzepatide | $250/mo (starting dose, compounded) | $329/mo (starting dose, compounded) |
| Coverage | 5 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #166 · C
Strengths
- Fully transparent pricing published on the website
- Semaglutide from $200/mo and tirzepatide from $250/mo
- Lab panels included with clinician-supervised dosing
- LegitScript certified clinic
- Lead PA-C with over a decade in obesity medicine
Where it loses points
- Telehealth limited to MO, IA, KS, UT, and WA
- Compounded GLP-1 only, not brand-name
- No insurance billing (cash-pay)
- PA-led rather than MD/DO-led
Graded #145 · C
Strengths
- LegitScript certified with active seal (ID 51177727)
- Semaglutide starting at $179/month with free shipping included
- 1:1 direct provider messaging and personalized titration plan in every plan
- Nutrition coaching included with the weight-loss program
- Provider review completed within 24 hours; no insurance required
Where it loses points
- Tirzepatide at $329/month starting is at the high end of the compounded market
- Compounding pharmacy not named on any public page
- No physician names or clinical leadership disclosed publicly
- Only 47 states covered — the 3 excluded states are not named on the site
- Labs not included in the weight-loss plan
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.