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Head-to-head · WeighScore

Optimized Health vs Tryozi

Optimized Health
Graded #175

Higher grade

vs+5.800000000000004
Tryozi
Graded #295

Lower grade

The verdict

Optimized Health takes it — 67.2/100 to 61.4/100.

Optimized Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Optimized Health is a concierge medical weight loss and hormone clinic offering clinician-supervised GLP-1 programs with compounded semaglutide and tirzepatide, plus oral options like phentermine.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationOptimized Health +11
75
64
Clinical oversightOptimized Health +2
76
74
Labs & monitoringOptimized Health +37
89
52
FulfillmentTryozi +23
67
90
Contract termsOptimized Health +6
55
49
Optimized Health · left barTryozi · right bar

The numbers

MetricOptimized HealthTryozi
WeighScore67.2/10061.4/100
GradeCC
Scorecard rank#175#295
Semaglutide$200/mo (starting dose, compounded)$279/mo (compounded)
Tirzepatide$250/mo (starting dose, compounded)$379/mo (compounded)
Coverage5 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Optimized Health

Graded #175 · C

Strengths

  • Fully transparent pricing published on the website
  • Semaglutide from $200/mo and tirzepatide from $250/mo
  • Lab panels included with clinician-supervised dosing
  • LegitScript certified clinic
  • Lead PA-C with over a decade in obesity medicine

Where it loses points

  • Telehealth limited to MO, IA, KS, UT, and WA
  • Compounded GLP-1 only, not brand-name
  • No insurance billing (cash-pay)
  • PA-led rather than MD/DO-led
Tryozi

Graded #295 · C

Strengths

  • Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
  • Price does not increase as your dose increases, stated plainly on the pricing page
  • Full total shown before payment, with the first-month discount and the ongoing rate both visible
  • States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
  • LegitScript certification verified against the issued seal, not just the badge

Where it loses points

  • Headline $139 is a first-month half-price offer; the ongoing rate is $279
  • Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
  • Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
  • No refund policy detail is published on the pricing page itself

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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