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Head-to-head · WeighScore

Open Water Rx vs Vytora Health

Open Water Rx
Graded #359

Lower grade

vs+13.5
Vytora Health
Graded #79

Higher grade

The verdict

Vytora Health takes it — 72.3/100 to 58.8/100.

Vytora Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueVytora Health +11
48
59
Dose & formulationOpen Water Rx +3
88
85
Clinical oversightVytora Health +42
54
96
Labs & monitoringOpen Water Rx +5
60
55
FulfillmentVytora Health +54
42
96
Contract termsOpen Water Rx +35
55
20
Open Water Rx · left barVytora Health · right bar

The numbers

MetricOpen Water RxVytora Health
WeighScore58.8/10072.3/100
GradeCC
Scorecard rank#359#79
Semaglutide$249/mo (compounded)$180/mo (all doses, compounded)
Tirzepatide$339/mo (compounded)$249/mo (all doses, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessYesYes
Oral / sublingualYesInjection only
Open Water Rx

Graded #359 · C

Strengths

  • Combines weight-loss and longevity verticals in one brand
  • Established brand domain

Where it loses points

  • Limited public data — most details are gated behind signup or rendered only in JavaScript
  • Pricing not disclosed
  • GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
  • States-served list not disclosed
  • Pharmacy partner not named
Vytora Health

Graded #79 · C

Strengths

  • All 50 states plus DC, with per-state video-vs-audio compliance disclosed
  • Both compounded and brand-name options on one platform — uncommon
  • LegitScript Approved and HIPAA compliant
  • Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
  • Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)

Where it loses points

  • Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
  • Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
  • Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
  • Initial consultation cost not shown on the public pricing page
  • Limited per-prescriber state licensure detail

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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