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Head-to-head · WeighScore

Onyx Weight Loss vs ZYP Medical

Onyx Weight Loss
Graded #359

Lower grade

vs+15.799999999999997
ZYP Medical
Graded #62

Higher grade

The verdict

ZYP Medical takes it — 74.6/100 to 58.8/100.

ZYP Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZYP Medical +37
43
80
Dose & formulationZYP Medical +19
64
83
Clinical oversightZYP Medical +11
75
86
Labs & monitoringOnyx Weight Loss +10
63
53
FulfillmentZYP Medical +13
53
66
Contract termsZYP Medical +6
55
61
Onyx Weight Loss · left barZYP Medical · right bar

The numbers

MetricOnyx Weight LossZYP Medical
WeighScore58.8/10074.6/100
GradeCC
Scorecard rank#359#62
Semaglutide$228/mo (starting dose, compounded)$150/mo
Tirzepatide$280/mo (starting dose, compounded)$233/mo
Coverage8 states6 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
ZYP Medical

Graded #62 · C

Strengths

  • Transparent flat-rate pricing including medication and shipping with no hidden fees
  • Low $50 initial one-hour consultation
  • Offers both injectable and oral tirzepatide options
  • No membership fees and pricing decreases as treatment progresses
  • Care from a board-certified family nurse practitioner

Where it loses points

  • Compounded medications are not FDA-approved
  • Available in only six states (NE, IA, SD, KS, CO, AZ)
  • Cash-pay only; no insurance noted
  • No named compounding pharmacy partner disclosed
  • No LegitScript certification shown on site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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