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Head-to-head · WeighScore

Onyx Weight Loss vs tru Weight Loss

Onyx Weight Loss
Graded #359

Lower grade

vs+0.10000000000000142
tru Weight Loss
Graded #356

Higher grade

The verdict

tru Weight Loss takes it — 58.9/100 to 58.8/100, but only just.

tru Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. tru Weight Loss (truhealthnow) is a physician-directed telehealth program prescribing compounded semaglutide and tirzepatide, shipped from US-licensed compounding pharmacies. Onyx Weight Loss is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueOnyx Weight Loss +5
43
38
Dose & formulationtru Weight Loss +8
64
72
Clinical oversighttru Weight Loss +1
75
76
Labs & monitoringtru Weight Loss +9
63
72
Fulfillmenttru Weight Loss +9
53
62
Contract termsOnyx Weight Loss +35
55
20
Onyx Weight Loss · left bartru Weight Loss · right bar

The numbers

MetricOnyx Weight Losstru Weight Loss
WeighScore58.8/10058.9/100
GradeCC
Scorecard rank#359#356
Semaglutide$228/mo (starting dose, compounded)$299/mo (all doses, 3-month plan, compounded)
Tirzepatide$280/mo (starting dose, compounded)$399/mo (all doses, 3-month plan, compounded)
Coverage8 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
tru Weight Loss

Graded #356 · C

Strengths

  • Flat, transparent pricing (299/mo semaglutide, 399/mo tirzepatide)
  • All-inclusive: consult, lab work, medication delivery, nutritionist and behavioral coaching
  • Directed by a named physician (Neha Grover, MD) from a physical clinic

Where it loses points

  • Requires a 3-month commitment before you can cancel
  • States served are not specified and the dispensing pharmacy is not named
  • Does not accept insurance, HSA, or FSA

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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